Norovirus, computer illustration. Norovirus is a genus of RNA (ribonucleic acid) viruses (of the family Caliciviridae), which cause about half of all gastroenteritis cases around the world. The disease is characterised by nausea, vomiting, diarrhoea and abdominal pain. The diarrhoea results in fluid loss and dehydration, which may become life-threatening in the young, the elderly, and the immunocompromised if not treated promptly.